REVIEW ARTICLE


Rapid Serological Testing for Managing the COVID-19 Pandemic: A Review



Sultan M. Faheem1, *, Jancie D’Mello2, Sultan M. Kaleem3, Burra V. L. S. Prasad 2, Khalid Siddiqui4
1 School of Life Sciences, Manipal Academy of Higher Education Dubai Campus, Dubai, United Arab Emirates
2 Department of Biotechnology, KLEF University, Vaddeswaram, Andhra Pradesh, India
3 Department of Maxillofacial Diagnostic Sciences, College of Dentistry, King Khalid University, Abha, Saudi Arabia
4 Strategic Center for Diabetes Research, College of Medicine, King Saud University, Riyadh, Saudi Arabia


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Creative Commons License
© 2021 Faheem et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the School of Life Sciences, Manipal Academy of Higher Education Dubai Campus, Dubai, United Arab Emirates; E-mail: faheemsm@manipaldubai.com


Abstract

With the onset of the novel coronavirus disease pandemic (COVID-19) that emerged from Wuhan in China, the need of the hour can be summarized into two groups. The first one is a potent vaccine as a prophylactic measure to prevent the virus from infecting people, and the second is a rapid diagnosis of the disease to help healthcare professionals and government authorities to plan and control the spread and provide effective care and treatment. This review delves into the latter, describing the COVID-19 and its treatment, including the race for an effective vaccine, and highlighting the role of serological testing in managing the pandemic since a well-designed study to understand mechanisms and serological correlations of protective immunity is crucial for rational clinical and public health policies. In conclusion, swift vaccination and response tactics, such as social distancing, hand hygiene, wearing of masks, and, if required, lockdown practices continue to be important in managing the pandemic while carefully monitoring any possible outbreak due to the variants.

Keywords: SARS-CoV-2, Pandemic, COVID-19, Serological testing, Seroprevalence, Vaccine.