REVIEW ARTICLE


Phage Therapy in the Treatment of Infectious Diseases: An Overview



Mahsa Jalili1, 2, Nastaran Ansari1, 2, 3, Somaye Bakhtiari1, 2, Farid Azizi Jalilian1, 2, 3, *
1 Research Center for Molecular Medicine, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
2 Educational, Research and Diagnostic Center For Emerging and Re-Emerging Viral Diseases, Hamadan University of Medical Sciences, Hamadan, Iran
3 Department of Virology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran


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Creative Commons License
© 2021 Jalili et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at Department of Virology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran; Tel: +989180189029; E-mails: azizifarid@gmail.com


Abstract

Today, we are facing the spread of antibiotic resistance in various microbial communities. Also, researchers are using new methods to replace conventional treatments to prevent chronic bacterial infections. Hence, the used of phages or bacterial contaminant particles are now used as an effective method in the treatment of many infectious diseases. Several studies have suggested that the use of bacteriophages is effective in treating some bacterial diseases. Therefore, the present study was performed to evaluate phage therapy studies against infections caused by bacterial infections. The use of bacteriophages as new targets in the treatment of bacterial diseases restricts the development of infectious diseases. Bacteriophages can provide a new perspective in the development of new drugs to reduce the rate of bacterial infections. Also, it seems more research should be done in this field and more developed techniques should be used to evaluation of new phages.

Keywords: Bacteriophages, Phage therapy, Bacterial infections, Infection, Antibiotic resistance, Review.