Urinary Biomarkers of Oxidative Stress in Atrial Fibrillation
Lei Mengǂ, 1, Ricko Wongǂ, 2, Man Yin Tsui3, Gary Tse4, 5, Guangping Li1, Tong Liu*, 1, Gregory Y. H. Lip6
Identifiers and Pagination:Year: 2018
First Page: 24
Last Page: 33
Publisher Id: TOBIOMJ-8-24
Article History:Received Date: 13/8/2018
Revision Received Date: 8/10/2018
Acceptance Date: 12/11/2018
Electronic publication date: 31/12/2018
Collection year: 2018
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: (https://creativecommons.org/licenses/by/4.0/legalcode). This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
There is increasing evidence from molecular studies to support the role of inflammation and increased oxidative stress that produce structural and electrical atrial remodeling to produce Atrial Fbrillation (AF). Oxidative damage to cardiomyocytes yields chemical substances that are secreted in urine. These substances can serve as biomarkers that can be measured, potentially allowing clinicians to quantify oxidative damage to the heart.