Indices Indicating Early Renal Microvascular Disease in Diabetes
N. Futrakul*, 1, P. Futrakul2
Identifiers and Pagination:Year: 2011
First Page: 18
Last Page: 20
Publisher Id: TOBIOMJ-4-18
Article History:Received Date: 15/09/2011
Revision Received Date: 26/10/2011
Acceptance Date: 29/10/2011
Electronic publication date: 28/12/2011
Collection year: 2011
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Renal microvascular disease is crucial to renal disease progression. Renal microvascular disease in late stage diabetic nephropathy is associated with defective angiogenesis and fails to respond to vasodilator treatment. Recognition of early renal microvascular disease is necessary, since in this stage, the vascular homeostasis is adequately functional and responsive to vasodilator treatment. Indices that can screen early renal microvascular disease include creatinine clearance or glomerular filtration rate, renal plasma flow or peritubular capillary flow and fractional excretion of magnesium (FE Mg).